By Lena M. Napolitano MD, Krishnan Raghavendran MD
This factor of serious Care Clinics will specialize in critical Acute respiration misery Syndrome and working with it within the ICU. subject matters will comprise: demanding situations and Successes in ARDS Research;Mechanical air flow with Lung protecting techniques: What works?; Gene treatment for ALI/ARDS;High Frequency Oscillatory air flow in ALI/ARDS;Prone positioning remedy in ARDS;Recovery and long term end result in ARDS; and Experimental versions and emergeing hypotheses for ALI and ARDS
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Additional info for ALI and ARDS: Challenges and Advances, An Issue of Critical Care Clinics (The Clinics: Internal Medicine)
Brower RG, Lanken PN, MacIntyre N, et al. ARDS Clinical Trials Network. Higher vs. lower positive end-expiration pressures in patients with the acute respiratory distress syndrome. N Engl J Med 2004;351(4):327–36. 7. Connors AF Jr, Speroff T, Dawson NV, et al. The effectiveness of right heart catheterization in the initial care of critically ill patients. JAMA 1996;276:889–97. 8. Bernard GR, Sopko G, Cerra F, et al. Pulmonary artery catheterization and clinical outcomes: National Heart, Lung, and Blood Institute and Food and Drug Administration workshop report.
Predictors of hospital mortality in a population-based cohort of patients with acute lung injury. Crit Care Med 2008; 36(5):1412–20. 100. Gajic O, Afessa B, Thompson BT, et al. Prediction of death and prolonged mechanical ventilation in acute lung injury. Crit Care 2007;11(3):R53. 101. Seeley E, McAuley DF, Eisner M, et al. Predictors of mortality in acute lung injury during the era of lung protective ventilation. Thorax 2008;63(11):994–8. 102. Villar J, Perez-Mendez L, Basaldua S, et al. Age, plateau pressure and PaO2/ FIO2 at ARDS onset predict outcome.
Futility” means there was no realistic chance that the intervention could be proved to be beneficial with the size of trial planned. ” The database for this study has been analyzed, and the report has been submitted for publication. ) The EDEN portion of the 2 Â 2 factorial design continues, as it has not been terminated by the DSMB. This portion of the trial was recently completed to determine whether early aggressive full feeding of patients with ALI will result in improved outcome as compared with a more conservative feeding strategy that provides only “token” calories for the first 6 days followed by full feeding in both arms thereafter.
ALI and ARDS: Challenges and Advances, An Issue of Critical Care Clinics (The Clinics: Internal Medicine) by Lena M. Napolitano MD, Krishnan Raghavendran MD